Altera Cyclone V SE FPGA (5CSEBA6U23I7) with 110,000LE (41,500ALM) and 5,570Kbit of Block RAM
ARM Cortex A9 dual-core CPU at 800MHz
HDMI video and audio allowing connect to any modern monitor/TV
DDR3 1GB available for both ARM and FPGA
High speed ARMFPGA interconnect due to both are in the same chip
Linux on ARM provides support for many I/O devices and file systems
Board is mass produced by a big manufactured and freely available for a relatively cheap price 130USD (99USD for students/professors)
Due to a larger FPGA, bigger systems can be created. It's also possible to add more support from ARM side. For example TZX tape format can be parsed on ARM and then send to FPGA. Firmware is not limited by code size or available RAM. It'e even possible to emulate some parts of system on ARM which is not available in FPGA (so-called hybrid emulator).
MiSTer scales original video resolution to a standard HDMI resolution (usually 1280x720p60), so you don't need to look for some ancient monitor with VGA input supporting non-standard resolution and frame rates. For purists VGA is still available and it outputs original video resolution.